Propolis: A Natural Aid for Blood Sugar and Lipid Management
2025-12-09
Extensive research highlights propolis, a natural resin collected by bees, for its potential in supporting healthy blood sugar and lipid levels.
Blood Sugar Regulation
Studies indicate that propolis from various geographical origins, while differing in specific flavonoid and phenolic acid content, generally exhibits beneficial effects on glucose metabolism. Research on type 2 diabetic models shows that propolis supplementation can significantly lower fasting blood glucose (FBG) and triglyceride (TG) levels while improving insulin sensitivity.
Synergistic effects are observed when propolis is combined with other substances. For instance, its combination with yogurt may inhibit glucose absorption and α-glucosidase activity. Studies also suggest enhanced benefits when paired with chromium compounds, showing superior effects in lowering FBG and improving glucose tolerance compared to individual use.
Furthermore, propolis shows promise in mitigating diabetes-related complications. Its antioxidant and anti-inflammatory properties are linked to protective effects against diabetic nephropathy (kidney damage) and improvements in markers associated with diabetic foot conditions.
Lipid Regulation
Propolis is recognized for its lipid-modulating properties, often termed a "vascular cleanser." Animal studies demonstrate that propolis extract can reduce body weight, visceral fat, liver weight, and serum levels of TG and cholesterol. It appears to work by inhibiting the expression of genes related to fatty acid synthesis, thereby countering diet-induced hyperlipidemia.
Combination therapies further enhance these benefits. Propolis combined with ingredients like American ginseng or thymoquinone (from black seed) has shown improved outcomes in lipid profiles, including increased HDL-C ("good" cholesterol) and reduced LDL-C ("bad" cholesterol) and TG, contributing to a lower risk of atherosclerosis.
In conclusion, scientific evidence supports the role of propolis as a valuable natural compound for metabolic health, primarily through its anti-hyperglycemic, lipid-lowering, antioxidant, and anti-inflammatory actions.
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